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For the 2025-26 school year, there are 4 public schools serving 2,839 students in Sanford, ME (there are , serving 224 private students). 93% of all K-12 students in Sanford, ME are educated in public schools (compared to the ME state average of 90%).

The top ranked public schools in Sanford, ME are Margaret Chase Smith, Sanford Pride Elementary School and Sanford Middle School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Sanford, ME public schools have an average math proficiency score of 44% (versus the Maine public school average of 49%), and reading proficiency score of 79% (versus the 84% statewide average). Schools in Sanford have an average ranking of 3/10, which is in the bottom 50% of Maine public schools.

Minority enrollment is 16% of the student body (majority Hispanic and Black), which is more than the Maine public school average of 14% (majority Black and Hispanic).