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For the 2025-26 school year, there are 2 public schools serving 836 students in Knox, PA (there are , serving 124 private students). 87% of all K-12 students in Knox, PA are educated in public schools (compared to the PA state average of 86%).

The top ranked public schools in Knox, PA are Keystone Elementary School and Keystone Jr. Sr. High School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Knox, PA public schools have an average math proficiency score of 44% (versus the Pennsylvania public school average of 38%), and reading proficiency score of 67% (versus the 55% statewide average). Schools in Knox have an average ranking of 7/10, which is in the top 50% of Pennsylvania public schools.

Minority enrollment is 3% of the student body (majority Hispanic), which is less than the Pennsylvania public school average of 39% (majority Hispanic and Black).